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Which PKD Is Worse: PKD 1 or 2

2014-12-07 01:49

Which PKD Is Worse: PKD 1 or 2Polycystic Kidney Disease (PKD) is a genetic disorder that can cause a cluster of cysts on kidney. There are two type: Autosomal Recessive Polycystic Kidney Disease (ARPKD) and Autosomal Dominant Polycystic Kidney Disease (ADPKD), which is also called PKD 1 and PKD 2. Which type is worse?

Get facts on PKD 1 and 2

PKD1 (ARPKD): It is a relatively rare genetic disorder, occurring approximately 1 in 20,000 individuals. It is easy to occur in both boys and girls. Symptoms usually occur in the first month after the birth.

PKD 2 (ADPKD): Compared with PKD 1, this type is more common, and affects approximately 1 in 500. It does not skip a generation. There is usually a family history of ADPKD. Parents with PKD 2 have a 50% chance of passing the disease on to each of their children.

Prognosis and life expectancy of PKD 1 and PKD 2

Both of the two types can cause some slight or severe symptoms that can be fatal. That is to say, you cannot say one type is worse than the other. Cases are different from individuals. The prognosis and life expectancy is determined by many factors such as age, physical health, medication history, and complications, etc.

In general, people with ADPKD (PKD 2)won’t see any symptoms before the age of 30. They can live another more 10 years after symptoms appear. About half of ADPKD patients develop Kidney Failure after 60 years old. Well then, How about children with ARPKD? Previously thought to be a fatal condition, the prognosis for children with ARPKD has improved dramatically. Twenty years ago, only half of the children born with the disease survived to their 10th birthday, but now that percentage has increased to 85 percent.


No matter which type of Polycystic Kidney Disease, timely treatment is always necessary and important, or they can be fatal. Control a diet to prevent some symptoms, taking medicines to relieve severe problems, and taking natural therapies to shrink kidney cysts should all be involved into your plan. You can email to us at for free suggestions.

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