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What Is The Natural Progression Of PKD

2013-05-14 16:42

Since PKD is a congenital and progressive kidney disease and unfortunately there is no effective treatment at present, therefore many patients are so scared and worried what will happen to them with the continuous enlargement and increase of renal cysts.

Here we will talk about the illness progression that PKD patients will experience since the diagnosis of the disease.

Since PKD is a hereditary disease, patients have renal cysts in their kidneys since birth, only that the cysts are small in size in the early stage and they cause no obvious symptoms or discomforts to the patients. Usually PKD will not be detected before the patient is 20 years. Since most PKD patients have family history of the disease, therefore it is necessary for the families of PKD patients to have early tests to rule out the possibility of PKD.

When the patients are between 30-40 years old, the cysts will experience rapid growth and some symptoms will develop such as high blood pressure, back pain, frequent urinary tract infections, etc.

When patients are at their 40s, the renal cysts will gain further growth. When the cyst is larger than 4cm, it has high risk to get rupture. Patients will suffer from more symptoms such as back pain, proteinuria, hematuria, etc. Renal functions will be impaired.

If the cysts continue to increase, it will oppress surrounding renal tissues and organs and cause ischemia and hypoxia in the kidneys. Some patients will experience cyst rupture if they do not pay much attention in their daily life. In case of cyst rupture, patients will be very painful and it can cause sharp decline of kidney functions or even threaten the patient’s life.

In the end, PKD will cause the loss of most kidney functions and enter into end stage renal disease. At this stage, dialysis or kidney transplant will be needed to sustain the patient’s life.

For PKD, western medicines usually adopt a wait and see attitude because they have no good treatment. Chinese medicines will adopt osmosis therapy to shrink the renal cysts and prevent further illness progression.

Tag: PKD Overview

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